Lichenoid lesion


Include a broad group of oral mucosa lesions which share clinical characteristics and histological criteria with Oral Lichen Planus (OLP); they are indicative of disease or different, localised conditions. The best known lichenoid lesions (LL) are:

  • LL from contact with dental material, specifically amalgam, presenting close to an amalgam filling. They are neither bilateral nor symmetrical and, in most cases, they heal following removal of the amalgam.
  • LL from drugs, specifically NSAIDs, ACE-inhibitors, hypoglycaemic drugs, penicillamine, biopharmaceutical and antineoplastic drugs (such as: Adalimumab, Imatinib, Sunitinib and Capecitabine).

Clinical and histological characteristics are very similar to those of OLP such that a differential diagnosis is not easy other than, with the agreement of the prescribing doctor, suspending treatment with suspect drug and a clinical amelioration is observed.

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